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Our core platform is supramolecular peptide structures, which contain thousands of biological signals that instruct cells to initiate regenerative processes and restore function lost from injury, disease, or aging. The peptides are completely biodegradable and tunable for different applications, enabling a range of therapies to repair bone, cartilage, muscle, and cardiovascular tissues, as well as promote neural regeneration in the brain and spinal cord.


These peptides form scaffolds that mimic the structure and dynamic nature of tissues found in our bodies, allowing them to better communicate with cells.

Therapeutic Applications

Amphix Bio's materials facilitating spine fusion

Bone Regeneration

Spinal Fusion Surgery

Spinal fusion surgery is used to treat back pain, the leading cause of disability, caused by degenerative disc disease, spondylolisthesis, scoliosis, stenosis, etc., with over 500K procedures per year in the US. Our bone regeneration therapy, a fully off-the-shelf bone graft substitute, enables surgeons to perform spine fusion procedures with fewer side effects.

Aligned neurons

Neural Regeneration

Spinal Cord Repair

Spinal cord injury (SCI) is a debilitating orphan condition with no approved treatments. It causes varying degrees of paralysis for the ~18K patients who experience acute SCI per year in the US. In preclinical studies, our injectable therapeutic regenerated spinal cord tissue and reversed paralysis when administered 24 hours after severe SCI.

Polymer nanofiber composite for cartilage regeneration

Cartilage Regeneration

Knee Cartilage Repair

Damaged knee cartilage due to age-related degeneration or traumatic injury can severely limit mobility and reduce quality of life, affecting ~1M patients per year in the US. Our injectable therapeutic can be used to augment standard-of-care surgeries and improve efficacy in repairing cartilage.

Key Publications

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